Immunomodulation & Immunother about Vaccine

The readings this week will provide a history and how this all got started through where the field is at today. One of the articles is specifically about adjuvants. Adjuvants play a big role. They ensure that you get the best response to the challenge as well as helping to steer the response to the compartment of the immune system you want. No sense in making antibodies if T cells are needed nor vice versa. The response needs to meet the needs of how the individual will be challenged. But, there is always a “but” in biology, adjuvants can also cause a great deal of inflammation that may lead to pathology and that in turn can lead to some nasty co-morbidities. Need to make sure the process justifies the means.

As you should expect there is a homework for the week. Design a vaccine strategy for Zika Virus. Include specific vaccine type and how and age group the vaccine would target (or be administered to). The ability to be brief indicates mastery of the material, you only get two paragraphs.

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